Name of the Procedure:

Common name: Strontium-89 Therapy Medical term: Strontium Sr-89 Chloride Therapy

Summary

Strontium Sr-89 Chloride Therapy is a medical treatment used for pain relief in patients with cancer that has spread to the bones. It involves the injection of a radioactive substance called strontium-89, which targets and helps alleviate bone pain caused by cancer.

Purpose

Medical Conditions:

• Bone metastases (cancer that has spread to the bones)

Goals and Expected Outcomes:

• Pain relief in affected bone areas
• Improve the quality of life for patients with advanced cancer

Indications

Specific Symptoms:

• Severe bone pain due to metastatic cancer

Patient Criteria:

• Diagnosed with cancer that has metastasized to the bones
• Experiencing significant pain unmanageable by other medications

Preparation

Pre-procedure Instructions:

• No specific fasting required
• Discontinue certain medications if advised by your doctor

Diagnostic Tests:

• Blood tests to check overall health and bone marrow function

Procedure Description

1. The patient receives an intravenous (IV) injection of strontium-89 chloride.
2. Strontium-89 circulates through the bloodstream and localizes in the bone tissue.

3. It emits radiation directly to the bone tumors, alleviating pain.

   Tools and Equipment:

   • IV injection equipment
   • Radiopharmaceutical (Strontium-89)

Anesthesia or Sedation:

• Not required

Duration

• The actual injection takes about 5-10 minutes.
• Pain relief may begin within 1 to 2 weeks after the injection.

Setting

• Performed in a hospital or an outpatient clinic with facilities to handle radioactive materials.

Personnel

• Oncologist
• Nuclear medicine specialist
• Registered nurse

Risks and Complications

Common Risks:

• Mild reactions at the injection site
• Temporary increase in bone pain (flare reaction)

Rare Complications:

• Lowered blood cell counts, potentially leading to increased risk of infection or bleeding
• Potential bone marrow suppression

Benefits

• Significant pain relief in bone metastases
• Improved mobility and quality of life
• Relief can last for several months

Recovery

Post-procedure Care:

• Hydration is encouraged
• Regular monitoring of blood counts

Expected Recovery Time:

• Minimal downtime required, most patients can continue with daily activities
• Follow-up appointments as recommended by the healthcare provider

Alternatives

Other Treatment Options:

• Oral or intravenous pain medications
• Radiation therapy
• Bisphosphonates (bone-strengthening drugs)

Pros and Cons of Alternatives:

• Pain medications may not provide long-lasting relief
• External radiation therapy can target specific bone areas but may not cover all painful sites
• Bisphosphonates can strengthen bones but may not offer immediate pain relief

Patient Experience

During the Procedure:

• Minor discomfort at the injection site
• Generally, no pain during the injection

After the Procedure:

• Potential slight increase in pain initially (flare reaction)
• Pain relief usually felt within 1-2 weeks and can last for several months
• Routine blood tests to monitor for side effects