Name of the Procedure:

Growth Stimulation Expressed Gene 2 (ST2, Interleukin 1 Receptor-Like 1) Testing

Summary

This test measures the levels of ST2 protein in the blood. ST2 is important in assessing heart health, particularly in patients with chronic heart failure. Elevated ST2 levels can indicate cardiac stress and inform treatment decisions.

Purpose

ST2 testing primarily addresses chronic heart failure. By measuring levels of ST2, healthcare providers can gain insights into the severity of the condition and predict potential complications, helping guide treatment plans.

Indications

• Chronic heart failure (CHF)
• Monitoring heart function
• Assessing risk of cardiovascular events

Preparation

• No specific fasting required.
• Patients should inform their healthcare provider about any medications they are currently taking.

Procedure Description

1. A blood sample is drawn from a vein, usually in the arm.
2. The sample is sent to a laboratory for analysis.
3. Enzyme-linked immunosorbent assay (ELISA) or other immunoassay techniques are used to measure ST2 levels.

Duration

The blood draw typically takes about 5-10 minutes. Lab analysis usually takes a few days.

Setting

The blood sample is usually drawn in a hospital, outpatient clinic, or a laboratory facility.

Personnel

• Phlebotomist or nurse for the blood draw.
• Laboratory technician or technologist to analyze the sample.
• Cardiologist or primary care physician interprets the results.

Risks and Complications

• Minimal risk associated with blood draw: slight bleeding, bruising, or infection at the puncture site.
• Rarely, some patients may feel dizzy or faint.

Benefits

• Provides crucial information for managing and treating chronic heart failure.
• Helps in risk stratification for potential cardiac events.
• Can lead to more personalized and effective treatment plans.

Recovery

• No significant recovery time required.
• Patients can resume normal activities immediately after the blood draw.

Alternatives

• NT-proBNP (N-terminal pro b-type natriuretic peptide) testing.
• Echocardiography.
• While alternatives exist, ST2 offers unique prognostic information that can complement other tests.

Patient Experience

• The process is similar to any standard blood test.
• Minor discomfort from the needle stick.
• Results discussion with a healthcare provider can help clarify the next steps in managing heart health.