Name of the Condition

• Steatocystoma Multiplex
• Also known as multiple sebaceous cyst syndrome.

Summary

Steatocystoma multiplex is a skin disorder characterized by the development of multiple, non-cancerous cysts filled with an oily substance known as sebum. These cysts commonly appear on the trunk, upper arms, armpits, and neck.

Causes

The condition is typically due to a genetic mutation in the keratin 17 (KRT17) gene, which affects the structural integrity of epithelial cells, leading to cyst formation.

Risk Factors

• Family history: Genetic predisposition is the main risk factor.
• Mutations in the KRT17 gene increase susceptibility to this condition.

Symptoms

• Presence of multiple yellowish cysts under the skin.

• Cysts may vary in size and can sometimes become inflamed, tender, or rupture.

  Diagnosis

• Physical examination: Initial assessment based on appearance.
• Biopsy: Histopathological examination of cyst tissue to confirm diagnosis.

Treatment Options

• Drainage or excision: Removal of cysts to prevent discomfort and reduce infection risk.
• Medications: Antibiotics for cyst infections and sometimes isotretinoin to decrease cyst number.

Prognosis and Follow-Up

• The condition is benign with no major health risks.
• Regular dermatological evaluations help manage new cysts and treat complications promptly.

Complications

• Potential for infection, inflammation, and rupture of cysts if not properly managed.

Lifestyle & Prevention

• While genetic causes cannot be prevented, infection risk can be minimized by maintaining good skin hygiene.
• Avoid squeezing or popping cysts to prevent infection.

When to Seek Professional Help

• Begin seeking help if cysts become painful, inflamed, infected, or rapidly increase in number.

Additional Resources

• American Academy of Dermatology (AAD) aad.org
• National Organization for Rare Disorders (NORD) rarediseases.org
• Dermatologic support communities and forums for patient advice and experiences.

Tips for Medical Coders

• Ensure that L72.2 is used specifically for cases diagnosed as Steatocystoma Multiplex.
• Beware of coding errors with similar cystic skin conditions; ensure diagnosis confirmation from medical records.