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Alloderm, per square centimeter

HCPCS code

Name of the Procedure:

Alloderm Application - AlloDerm Regenerative Tissue Matrix, per square centimeter (HCPCS Q4116)

Summary

AlloDerm is a type of regenerative tissue matrix used in various reconstructive surgeries. It is derived from donated human dermis, processed to remove cells while retaining the structural proteins. This creates a scaffold that can be incorporated into the patient's own tissue to support healing and regeneration.

Purpose

AlloDerm is primarily used for:

  • Reconstructive surgeries requiring tissue support or augmentation
  • Soft tissue repair
  • Enhancing wound healing

The procedure aims to improve tissue integration, reduce inflammation, and expedite healing, particularly in areas where natural tissue is deficient or damaged.

Indications

AlloDerm application is indicated for:

  • Breast reconstruction post-mastectomy
  • Soft tissue defects or deficiencies
  • Hernia repairs
  • Oral and maxillofacial surgeries

Patients suitable for the procedure typically have specific tissue defects or need structural support that autografts or other synthetic materials can't adequately provide.

Preparation

Patients may be advised to:

  • Fast for a specified period if general anesthesia is used
  • Adjust or discontinue certain medications (e.g., blood thinners)
  • Undergo pre-procedure assessments such as blood tests or imaging studies to evaluate the tissue deficit and plan the surgery.

Procedure Description

  1. Anesthesia: Local or general anesthesia is administered depending on the extent of the procedure.
  2. Incision: A surgical incision is made at the target site.
  3. Preparation: The AlloDerm graft is rehydrated and tailored to fit the defect.
  4. Placement: The graft is placed into the tissue defect and secured with sutures or other fixation methods.
  5. Closure: The incision is closed, and appropriate dressings are applied.

Duration

The procedure duration can vary widely based on complexity but typically ranges from 1 to 3 hours.

Setting

AlloDerm application is usually performed in a hospital operating room or an outpatient surgical center.

Personnel

  • Surgeon (often a plastic or reconstructive specialist)
  • Surgical nurse
  • Anesthesiologist (if general anesthesia is used)

Risks and Complications

Common risks include:

  • Infection
  • Graft rejection
  • Scarring

Rare complications may involve:

  • Delayed graft integration
  • Chronic pain at the incision site
  • Adverse reaction to anesthesia

Benefits

The benefits of using AlloDerm include:

  • Improved tissue repair and regeneration
  • Reduced inflammation compared to synthetic materials
  • Improved cosmetic and functional outcomes

Patients often start to see the healing benefits within weeks, with full integration occurring over several months.

Recovery

Post-procedure care may include:

  • Pain management with prescribed medications
  • Keeping the surgical site clean and dry
  • Avoiding strenuous activities for a specified period

Recovery times vary but usually range from several weeks to a few months. Follow-up appointments are essential to monitor the integration and healing of the graft.

Alternatives

Other treatment options include:

  • Autografts (using the patient's own tissue)
  • Synthetic meshes or scaffolds
  • Primary closure without grafts

Each alternative has its pros and cons, with autografts offering natural integration but requiring additional surgery, and synthetic meshes posing a higher risk of inflammation.

Patient Experience

During the procedure, patients under general anesthesia will be unconscious and feel nothing, while those under local anesthesia may feel pressure but no pain. Post-procedure, some discomfort or pain is expected, which can be managed with medications. Patients may experience swelling and bruising at the site, with gradual improvement as healing progresses.

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