Name of the Procedure:

• Common Name: Histrelin Implant
• Technical Term: Vantas, 50 mg (HCPCS Code: J9225)

Summary

The Histrelin implant, marketed under the brand name Vantas, is a small, flexible rod implanted under the skin to release medication over time. It is commonly used to treat hormone-sensitive conditions by delivering a steady dose of histrelin acetate.

Purpose

The Histrelin implant primarily addresses hormone-responsive conditions such as advanced prostate cancer. The goal is to reduce the levels of testosterone in men, thereby slowing the growth of prostate cancer cells.

Indications

• Advanced prostate cancer
• Symptoms like urinary difficulties or bone pain due to prostate cancer
• Patients who require long-term hormone therapy

Preparation

• Pre-procedure consultation to discuss medical history
• Blood tests to check hormone levels
• Instructions to avoid eating or drinking for a few hours prior

Procedure Description

1. Local anesthesia is administered to numb the area.
2. A small incision is made, typically in the upper arm.
3. The Histrelin implant is inserted just under the skin.
4. The incision is closed with sutures or surgical tape.
5. A dressing is applied to keep the area clean.

Duration

The procedure typically takes about 15 to 30 minutes.

Setting

The procedure is usually performed in an outpatient clinic or a doctor's office.

Personnel

• Physician (usually a urologist or oncologist)
• Nurse or medical assistant for support

Risks and Complications

• Common: Minor pain or swelling at the implant site, bruising, infection.
• Rare: Allergic reactions, implant breakage or displacement.

Benefits

• Provides continuous hormone therapy for up to 12 months.
• Reduces symptoms of prostate cancer.
• Minimizes the need for frequent hormone injections.

Recovery

• Keep the insertion site dry for 24 hours.
• Avoid strenuous activities for a few days.
• Follow-up appointments to monitor the implant and hormone levels.

Alternatives

• Oral hormone therapy
• Monthly or quarterly hormone injections
• Surgical removal of the testes (orchiectomy)
• Pros: Alternatives might require less invasive procedures but need more frequent dosing.
• Cons: Alternatives may have varying efficacy and side effect profiles.

Patient Experience

During the procedure, patients may feel local pressure but should not experience significant pain due to local anesthesia. Post-procedure, mild discomfort and swelling are common, but pain is generally minimal and can be managed with over-the-counter pain relievers.