Injection, aripiprazole, extended release, 1 mg
HCPCS code
Name of the Procedure:
Injection, aripiprazole, extended release, 1 mg (J0401)
Common name(s): Abilify Maintena injection, Aripiprazole extended-release injection
Summary
Aripiprazole extended-release injection is a long-acting antipsychotic medication administered via injection. It is designed to release the active drug gradually over time, offering patients with psychiatric conditions a more consistent and manageable treatment method compared to daily oral medications.
Purpose
Aripiprazole extended-release injection is primarily used to treat schizophrenia and bipolar I disorder.
- Goals:
- Stabilize mood
- Reduce symptoms such as hallucinations and delusions
- Improve overall functioning and quality of life.
Indications
- Chronic schizophrenia
- Maintenance treatment of bipolar I disorder
- Patients who have difficulty adhering to daily medications
Patient Criteria:
- Diagnosed with schizophrenia or bipolar I disorder
- History of non-adherence to oral medication
- Requires long-term antipsychotic medication
Preparation
- Pre-procedure instructions:
- Inform the patient about the procedure and potential side effects
- Review current medications
- May require baseline lab tests (e.g., liver function, blood glucose)
- Diagnostic Tests or Assessments:
- Psychiatric evaluation
- Review of medical history
Procedure Description
Step-by-Step Process:
- The patient usually lies down or sits in a comfortable position.
- The injection site (buttocks or deltoid muscle) is cleaned with an antiseptic.
- A healthcare provider administers a dose of aripiprazole extended-release via intramuscular injection.
- Post-injection site monitored briefly for any immediate reaction.
Tools and Equipment:
- Syringe and needle
- Antiseptic wipes
Anesthesia/Sedation: Not typically required
Duration
The injection process usually takes about 5-10 minutes.
Setting
This procedure is performed in an outpatient clinic or healthcare provider’s office.
Personnel
- Nurse or physician to administer injection
- Physician to supervise the overall treatment plan
Risks and Complications
Common Risks:
- Injection site reactions (pain, redness, swelling)
- Weight gain
- Drowsiness
- Gastrointestinal upset
Rare Complications:
- Neuroleptic malignant syndrome
- Tardive dyskinesia
- Severe allergic reaction
Management: Monitoring and symptomatic treatment for side effects; Immediate medical attention for severe reactions.
Benefits
Expected Benefits:
- Improved psychiatric symptoms stability
- Reduced relapse rates
- Better adherence to treatment
Timeline: Symptom improvement can be noticed within a few weeks, with continuous benefits over the long-term course of treatment.
Recovery
Post-procedure care:
- Monitor injection site for any severe reactions
- Follow-up appointments for monitoring efficacy and side effects
Recovery Time: Usually minimal; normal activities can be resumed almost immediately.
Restrictions: None specific, but the patient should report any unusual symptoms or side effects.
Alternatives
- Other Treatment Options:
- Oral antipsychotic medications
- Other injectable antipsychotics
- Psychotherapy and counseling
Pros and Cons:
- Oral Medications: Greater flexibility, but adherence may be challenging.
- Other Injectables: Different side effect profiles, varying durations of action.
Patient Experience
- During the Procedure: Mild discomfort at the injection site.
- After the Procedure: Possible mild soreness or redness at the injection site, which usually resolves quickly. Some patients may experience mild side effects as their body adjusts. Pain management includes over-the-counter pain relievers if necessary.
Comfort measures such as ensuring the patient is calm and relaxed before the injection can help reduce anxiety and discomfort.