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Ambulatory continuous glucose monitoring of interstitial tissue fluid via a subcutaneous sensor for a minimum of 72 hours; analysis, interpretation and report

CPT4 code

Name of the Procedure:

Ambulatory Continuous Glucose Monitoring (CGM) of Interstitial Tissue Fluid via a Subcutaneous Sensor, Analysis, Interpretation, and Report.


Ambulatory Continuous Glucose Monitoring (CGM) involves placing a small sensor under the skin to measure glucose levels in the interstitial fluid over at least 72 hours. The collected data is then analyzed and interpreted by a healthcare professional to provide a detailed report of glucose patterns and fluctuations.


CGM helps manage diabetes by offering detailed insights into glucose levels throughout the day and night. It aims to improve blood sugar control, reduce the risk of hypoglycemia and hyperglycemia, and provide data to adjust treatments more effectively.


CGM is indicated for individuals with diabetes, particularly those who experience frequent fluctuations in blood sugar levels, hypoglycemia unawareness, or difficulty controlling blood sugar with standard monitoring methods. It is suitable for both Type 1 and Type 2 diabetes patients.


  • The patient may need to avoid applying lotions or creams to the sensor insertion site before the procedure.
  • Sometimes, a brief skin cleansing may be needed.
  • The patient should discuss any medications or conditions that might affect sensor accuracy with their healthcare provider.

Procedure Description

  1. The healthcare provider selects the sensor insertion site, usually on the abdomen or the upper arm.
  2. The skin is cleaned, and the sensor is inserted just under the skin using a small applicator.
  3. A transmitter is attached to the sensor to send glucose readings wirelessly to a monitoring device.
  4. The patient carries the monitor or uses a compatible mobile device to receive real-time glucose data.
  5. After at least 72 hours, the sensor is removed, and the stored data is downloaded for analysis.
  6. A healthcare professional reviews the data and provides a detailed report, including trends, averages, and recommendations for treatment adjustments.


The sensor needs to be worn for at least 72 hours; the insertion process typically takes about 30 minutes.


The procedure can be performed in an outpatient clinic or a healthcare provider's office.


Nurses, diabetes educators, or other trained healthcare professionals typically perform the sensor application and data analysis.

Risks and Complications

  • Common risks include mild skin irritation or discomfort at the sensor site.
  • Rare complications might involve infection at the insertion site or sensor malfunction.
  • Any concerns can often be managed by adjusting sensor placement or seeking medical advice.


  • Continuous monitoring provides a comprehensive understanding of glucose levels, aiding precise treatment adjustments.
  • Reduced risk of undetected hypoglycemia or hyperglycemia.
  • Improved overall blood glucose control and reduced long-term complications from diabetes.


  • Minimal recovery time; patients can typically resume normal activities immediately.
  • The insertion site should be kept clean and dry.
  • Follow-up appointments may be scheduled to discuss the data and make necessary treatment adjustments.


  • Traditional self-monitoring of blood glucose using finger-stick tests.
  • Flash glucose monitoring systems.
  • The pros of CGM include more comprehensive data and reduced need for finger-sticks, while its cons might include cost and the need for wearing a sensor continuously.

Patient Experience

  • During sensor insertion, the patient may feel a slight pinch or discomfort.
  • While wearing the sensor, patients often forget it's there after an initial adjustment period.
  • Some mild skin irritation might occur around the insertion site.
  • Real-time data helps patients make immediate lifestyle and dietary adjustments to manage their glucose levels effectively.

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