Name of the Procedure:

Cholinesterase; serum
Common Name(s): Serum cholinesterase test, Pseudocholinesterase test

Summary

The cholinesterase serum test measures the levels of cholinesterase enzymes in your blood. These enzymes help break down certain types of medications and toxins. This test is commonly used to check for poisoning due to organophosphates or to diagnose pseudocholinesterase deficiency.

Purpose

• Medical Condition: Identifies poisoning due to organophosphates (commonly found in pesticides).
• Goals/Outcomes: Diagnose pseudocholinesterase deficiency, a condition which can increase sensitivity to certain anesthetics, and monitor individuals exposed to organophosphates to prevent toxicity.

Indications

• Symptoms/Conditions: Muscle weakness, difficulty breathing, drooling, confusion, seizures.
• Patient Criteria: Patients exposed to organophosphates or those who have experienced prolonged effects of certain muscle relaxant medications during surgery.

Preparation

• Instructions: No specific fasting required. Inform your healthcare provider about any medications you're taking as some can affect test results.
• Diagnostic Tests/Assessments: No additional tests required unless specified by your healthcare provider.

Procedure Description

1. Blood Sample Collection: A healthcare provider will draw a sample of blood from a vein in your arm using a needle.
2. Tools/Equipment: Sterile needle, syringe, tourniquet, antiseptic wipe, blood collection tube.
3. Anesthesia/Sedation: None required.

Duration

The procedure typically takes about 5-10 minutes.

Setting

The test is usually performed in a hospital lab, outpatient clinic, or diagnostic center.

Personnel

A phlebotomist or a nurse typically performs the blood draw.

Risks and Complications

• Common Risks: Slight discomfort at the needle site, minor bruising.
• Rare Risks: Infection at the needle site, excessive bleeding, fainting.

Benefits

• Expected Benefits: Identifies enzyme deficiencies and potential toxicities, allowing for appropriate treatment.
• Timeline: Test results are usually available within a few days.

Recovery

• Post-Procedure Care: Apply pressure to the draw site to prevent bleeding and bruising.
• Recovery Time: Immediate, with no restrictions.
• Follow-Up: Consult your healthcare provider for interpretation of results and further action.

Alternatives

• Other Options: Urine tests for organophosphate poisoning.
• Pros/Cons: Serum test is more specific and accurate for enzyme levels compared to urine tests.

Patient Experience

• During Procedure: Minimal pain or discomfort from needle insertion.
• After Procedure: Slight soreness or bruising at the draw site, manageable with over-the-counter pain relief or a cold compress.