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Meningococcal polysaccharide vaccine, serogroups A, C, Y, W-135, quadrivalent (MPSV4), for subcutaneous use

CPT4 code

Name of the Procedure:

Meningococcal polysaccharide vaccine, serogroups A, C, Y, W-135, quadrivalent (MPSV4), for subcutaneous use

Summary

The meningococcal polysaccharide vaccine (MPSV4) is a shot given under the skin to protect against four types of meningococcal bacteria (serogroups A, C, Y, and W-135). These bacteria can cause serious infections, like meningitis.

Purpose

Medical Condition or Problem Addressed:

Meningococcal disease, including meningitis and bloodstream infections.

Goals or Expected Outcomes:

To prevent infection caused by Neisseria meningitidis serogroups A, C, Y, and W-135, reducing the incidence of serious complications or death associated with these infections.

Indications

Symptoms or Conditions:
  • Individuals living in or traveling to areas where meningococcal disease is common.
  • Persons at increased risk due to certain medical conditions or treatments.
  • College students, military recruits, and laboratory personnel who might be exposed to the bacteria.
Patient Criteria:
  • Typically administered to individuals aged 2 years and older.
  • Recommended for people at high risk of exposure to meningococcal bacteria.

Preparation

Pre-procedure Instructions:
  • No specific fasting or dietary restrictions are required.
  • Inform the healthcare provider of any ongoing medications or existing health conditions.
  • Diagnostic tests are usually not required; however, a health history and physical assessment may be conducted.

Procedure Description

  • The vaccine is administered subcutaneously, usually in the upper arm.
  • The healthcare provider cleans the skin with an antiseptic.
  • A small needle is injected under the skin to deliver the vaccine.
  • Dressing the area with a bandage if necessary.
Tools and Equipment:
  • Syringe and needle
  • Antiseptic wipe
  • Bandage
Anesthesia or Sedation:
  • None required, though a topical numbing agent can be used for pain management if needed.

Duration

The procedure takes only a few minutes.

Setting

The vaccine can be administered in a doctor's office, clinic, pharmacy, or public health department.

Personnel

The procedure is typically performed by a nurse or other trained healthcare professional.

Risks and Complications

Common Risks:
  • Pain at the injection site
  • Redness, swelling, or a mild fever
Rare Risks:
  • Severe allergic reactions (anaphylaxis)
  • Guillain-Barré Syndrome (extremely rare)
Management:
  • Treat mild side effects with over-the-counter pain relievers and cold compresses.
  • Seek immediate medical attention for severe allergic reactions.

Benefits

Expected Benefits:
  • Provides immunity against four major serogroups of meningococcal bacteria.
  • Reduces the risk of severe infections like meningitis and sepsis.
Timeline for Benefits:
  • Immunity typically develops within a few weeks post-vaccination.

Recovery

Post-procedure Care:
  • Monitor for any adverse reactions for several hours after receiving the vaccine.
  • Avoid strenuous activity for a day or two if the injection site is sore.
Recovery Time:
  • Immediate routine activities can usually be resumed.
  • Minor side effects typically resolve within a few days.
Follow-up:
  • No specific follow-up appointments are required unless adverse reactions occur.

Alternatives

Other Options:
  • Meningococcal conjugate vaccine (MCV4), which may offer longer-lasting protection.
  • Antibiotic prophylaxis in high-risk exposure scenarios (not typically used for long-term prevention).
Pros and Cons:
  • MPSV4 is effective but may need re-vaccination for prolonged immunity.
  • MCV4 might provide longer durability but is also given by injection and has similar side effects.

Patient Experience

During the Procedure:
  • A quick pinch or stinging sensation at the injection site.
After the Procedure:
  • Possible mild soreness at the injection site.
  • Symptoms like a mild fever or tiredness may occur but usually resolve quickly.
Pain Management:
  • Over-the-counter pain relievers for injection site discomfort.
  • Cold compresses to reduce swelling or pain.

By understanding the details and implications of the MPSV4 procedure, patients can better prepare for and manage their vaccination experience.

Medical Policies and Guidelines for Meningococcal polysaccharide vaccine, serogroups A, C, Y, W-135, quadrivalent (MPSV4), for subcutaneous use

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