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Oncoprotein; des-gamma-carboxy-prothrombin (DCP)

CPT4 code

Name of the Procedure:

Oncoprotein; des-gamma-carboxy-prothrombin (DCP) Test Common Names: DCP Test, PIVKA-II (Protein Induced by Vitamin K Absence-II)

Summary

The DCP test measures the levels of des-gamma-carboxy-prothrombin in the blood, a protein typically produced by liver cancer cells. It's a simple blood test aimed at helping diagnose liver cancer, especially hepatocellular carcinoma (HCC).

Purpose

The primary purpose of the DCP test is to help diagnose liver cancer, particularly hepatocellular carcinoma (HCC). It is used in conjunction with other diagnostic tools to provide a more comprehensive picture of liver health. The goal is to detect liver cancer early, thereby increasing the chances of successful treatment.

Indications

  • Patients with chronic liver diseases like hepatitis B or C.
  • Patients with cirrhosis.
  • Individuals with a family history of liver cancer.
  • Elevated alpha-fetoprotein (AFP) levels where HCC is suspected.

Preparation

  • No special preparation is required.
  • Patients should inform their doctor about any medications they are taking, as some may affect test results.
  • Fasting is usually not necessary, though it's best to follow specific instructions from the healthcare provider.

Procedure Description

  1. Blood Sample Collection: A healthcare professional will draw blood from a vein in the patient's arm using a sterile needle.
  2. Sample Processing: The blood sample is then sent to a laboratory where it is analyzed for DCP levels.

Duration

The blood draw itself typically takes less than 5 minutes. Lab results may take a few days to a week.

Setting

The procedure is performed in a healthcare provider's office, outpatient clinic, or hospital lab.

Personnel

  • Phlebotomist or nurse for drawing the blood.
  • Laboratory technicians for analyzing the sample.
  • Physician to interpret the results.

Risks and Complications

  • Minor bruising or discomfort at the needle insertion site.
  • Rarely, infection or prolonged bleeding at the puncture site.

Benefits

  • Helps in the early detection of liver cancer, particularly hepatocellular carcinoma (HCC).
  • Can be used to monitor the effectiveness of ongoing liver cancer treatment.
  • Provides additional information to supplement other diagnostic tools.

Recovery

  • No significant recovery time is needed.
  • Patients can resume normal activities immediately after the blood draw.

Alternatives

  • Alpha-fetoprotein (AFP) Test: Another blood test used to detect liver cancer.
  • Imaging Tests: Ultrasound, CT scans, or MRI may also be used to detect liver abnormalities.
  • Liver Biopsy: Invasive procedure but can provide a definitive diagnosis.

Patient Experience

  • Minor discomfort from the needle prick during blood draw.
  • Some patients may experience mild anxiety, which can be managed with reassurance from healthcare personnel.
  • No significant pain after the procedure, and normal activities can be resumed immediately.

Medical Policies and Guidelines for Oncoprotein; des-gamma-carboxy-prothrombin (DCP)

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