80199 Tiagabine

Name of the Procedure:

Tiagabine Hydrochloride Therapy
Common name: Tiagabine
Medical term: Antiepileptic Drug (AED) therapy

Summary

Tiagabine is a medication used to help manage and control seizures in individuals with epilepsy. It works by increasing the levels of a calming neurotransmitter in the brain to prevent the excessive electrical activity that leads to seizures.

Purpose

Medical condition: Epilepsy, specifically partial seizures.
Goals:

• Reduce the frequency and severity of seizures.
• Improve the overall quality of life by minimizing seizure-related disruptions.

Indications

• Partial seizures with or without secondary generalization.
• Patients who have not responded adequately to other antiepileptic medications.

Preparation

• No specific fasting required.
• Patients may need to adjust other medications under the guidance of their healthcare provider.
• Regular blood tests for liver function and complete blood count may be recommended prior to starting therapy.

Procedure Description

1. Initial Assessment: A thorough medical history and evaluation by a neurologist.
2. Dosage: Tiagabine is taken orally, usually starting at a low dose and gradually increasing.
3. Routine Monitoring: Periodic follow-ups to adjust the dose and monitor for side effects.
   • Tools: Oral medication, typically in tablet form.
   • Anesthesia or Sedation: Not applicable.

Duration

• Initial dose adjustment period: Several weeks to months, with long-term use as maintenance therapy.

Setting

• Administered at home after prescription from a healthcare provider.
• Regular follow-up visits at a clinic or hospital.

Personnel

• Neurologist
• Primary care physician
• Nurse (for follow-up and monitoring)

Risks and Complications

• Common: Dizziness, somnolence, nervousness, and gastrointestinal disturbances.
• Rare: Severe rash, depression, suicidal thoughts, allergic reactions.
• Management: Regular monitoring, dose adjustments, and immediate medical attention if severe side effects occur.

Benefits

• Significant reduction in the frequency and intensity of seizures.
• Improvement in daily functioning and quality of life.
• Benefits typically noticed within several weeks of reaching the effective dose.

Recovery

• Tiagabine does not require a "recovery" period.
• Patients should adhere to prescribed dosages and attend scheduled follow-up appointments.
• Avoid operating heavy machinery or engaging in risky activities until medication effects are known.

Alternatives

• Other antiepileptic drugs (e.g., lamotrigine, levetiracetam).
• Vagus nerve stimulation or ketogenic diet in refractory cases.
• Pros: Some alternatives may have different side effect profiles or be more effective in certain individuals.
• Cons: Alternatives may have similar or new side effects and require regular monitoring.

Patient Experience

• Patients might initially feel drowsy or dizzy as the body adjusts to the medication.
• Regular check-ins with their physician to manage and mitigate any side effects.
• Pain management is generally not required, but patients should communicate any discomfort to their healthcare provider for management tips.